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Zyban
Brand Name: Zyban
Generic Name: Bupropion Hydrochloride [HCl]

Zyban [Bupropion HCl] Description

Bupropion HCl is an aminoketone; at first it was prescribed to treat depression, but later began to be used as an aid for cessation of smoking.

Bupropion prevents the reuptake of norepinephrine and dopamine in the brain, and is an α3β4-nicotinic receptor antagonist. It's action is believed to reduce the craving for nicotine as well as withdrawal symptoms.

Uses of Zyban

It helps people who want to stop smoking. The medicine is recommended for 7-12 weeks, though some people have stopped smoking within 10 days of this therapy, while others have taken it for a few months. It is meant for adults: who smoke 10 or more cigarettes in a day.
Zyban is not recommended for use in children below 18.

How to Use Zyban

Usually two doses have to be taken daily, but for patients with severe liver cirrhosis, a dose of 150mg is recommended every alternate day. Take the dose exactly as prescribed by your doctor. It can be taken with water, with or without meals, and should be swallowed whole.

Missed Dose of Zyban

Consult your doctor if you miss a dose. If you do miss a dose, then try to take the missed dose as soon as you can, but if time is nearing for the next dose, then leave the missed dose and take the regular one; don't double your dose.

Side-effects of Zyban

Some of the common, less serious side effects may include:-
  • Insomnia
  • Headaches/migraines
  • Dry mouth
  • Nausea, maybe even vomiting
  • Dizziness
  • Constipation
  • Diarrhea
  • Nervousness/anxiety
  • Tremors
  • Blurred vision
  • Cough, or sore throat
  • Runny nose, or sinus problems
  • Joint/muscular pain
  • Loss of libido

An allergic reaction such as:- itching, rash, any unexplained swelling, wheezing, difficulty in breathing/swallowing, or severe dizziness means that you should stop the medicine and ask your doctor for help.

Overdose of Zyban

Overdose symptoms can include: seizures, hallucinations, fainting, tachycardia, arrhythmias, labored breathing, hypotension, or coma. US residents can call the US national poison hotline at 1-800-222-1222. If the victim collapses or stops breathing, call local emergency services at 911.

Interactions of Zyban

Some of the medicines with which Bupropion interacts, are:-
  • Anti-seizure medicines like Carbamazepine
  • Medicines for cancer such as Cyclophosphamide
  • SSRIs like Paroxetine, Sertraline, or Norfluoxetine
  • Sedatives such as Diazepam
  • MAOIs like Phenelzine, Rasagiline, or Selegiline
  • Antipsychotics such as Chlorpromazine, or Thioridazine
  • Tricyclic antidepressants like Amitriptyline, or Imipramine
  • Medicines for arrhythmias such as Flecainide, or Propafenone
  • Heart medicines for preventing blood-clotting like Clopidogrel
  • Medications for asthma & COPD such as Theophylline
  • Anticholinergic drugs like Orphenadrine

Storage of Zyban

After you buy Zyban, store it at room temperature, safe from heat, light and dampness. Keep it out of reach of children and pets.

Precautions of Zyban

  • Those who drive or perform tasks requiring them to be fully alert should refrain from such activities, until they are aware of how this drug affects them and are sure of handling its’ effect.
  • When you purchase Zyban and start therapy, set a date for yourself to stop smoking after 1 week of taking the medicine if you face problems in quitting even after taking the medicine for 7 weeks, then consult your doctor.
  • Those who continue to take Zyban for sometime after ceasing to smoke, are more likely not to begin smoking again.
  • It is recommended that you do not attempt to treat yourself by taking, increasing, decreasing, or stopping the medicine on your own.
  • Never share your medicine with anyone else, even if they have similar symptoms it can do more harm than good to that person.

Notes of Zyban

Read the Patient Information every time you buy a refill - it may have some new information. Your physician will be able to tell you more about the USes, side effects, interactions, and precautions associated with this medication. Discard any unused medicine after treatment is over.